IPhone not connecting to iTunes anyone else?

For the last 2 months I believe? I have not been able to sync any of my apple devices to iTunes. The computer pops up that there's a device and the phone charges and all that but it does not come up in iTunes at all. I recently upgraded my iPhone 6 to the 6s plus and it still does not connect. I have tried uninstalling iTunes and reinstalling it, I've updated my phone to whatever the newest iPhone update is, my computer is up to date with the most recent Windows 10 software, I've even gone into to apple device support in the computer and everything is functioning as it should and none of it has worked. Is this just a bug in the DNA? Are others having this problem?

I have had this problem before and I fixed it by changing the lead that you use to connect the device if that does't work then i don't know how to fix it sorry