Any suggestions on how to fix low Iphone 5 signal?

So i have an Iphone 5 and on Saturday afternoon i realised my phone had low signal and at this time it wouldn't connect to Wi-Fi, A couple of days later i was looking at some forums to see if anyone else had the same problem and the things i read were that certain apps can reduce signal, So i deleted all the apps i had downloaded recently & it also said having a thick case can reduce signal, I had just brought a new case on the saturday and it was really thick and heavy so i took it off and my phone went back to normal.
A couple of days later i got a new case and i put it on and everything was working fine still but then that evening (last night) my phone signal reduced again to only one bar, Two if i was lucky. I tried connecting to Wi-Fi this time and it works with good signal aswell but still only one maybe two bars on my phone, I tried taking the case off but its still the same, although i can get a 3rd bar for a few seconds, I've deleted all recently downloaded apps again but now its still not working?
anyone have any suggestions?

Clean the inside of the phone by taking the back off and make sure the battery is fine.

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