Is it safe to update my Iphone 4s to IOS 6?

Is it safe to update my Iphone 4s to IOS 6?

Yes completely safe, IOS 6 is a lot better than previous versions.

Yes is safe but only if you have the original ios 6 but what i would do is jailbreak it jailbreak from greenpoison is safe i have it my self http://greenpois0n.com/

Yes, absolutely safe with iTunes.

Sure. Do a back up on itunes first though and update using your phone.
1. Connect the phone your computer
2.of corse open itunes
3.click on your phone in devices in the left corner
4. Make sure the summary tab @ the top of itunes is selected
5.under the back up selection select backup to this computer
6.sync it

Then go to general in on your phone, and go to software. Click update and let it do its thing.everything should be fine.
(if you don't do the backup there's a very good chance you could lose everything on it.)