Mobile code for USA from UK?

I want to send my friend a message from my iPad to their iPhone but when I enter their number it doesn't recognise it, I'm guessing I need to add some sort of code at the beginning like here in UK I think it's +44 or something like that I'm not sure but if someone could shed some light on this subject I would be very grateful.

The code for the UK is +44, you take the leading zero of their number.

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