Not able to sync my iTunes with my iPhone 4s?

I've read and tried every single thing in the support section about everything having to do with syncing and it still does not work. I'm trying to sync my iTunes stuff to my iPhone 4s and the sync button is grayed out and its not click-able. I set it up to sync over Wi-Fi and made sure I did everything they said to do in the support section. Then I tried to sync manually but when I clicked and dragged my songs over to my iPhone it didn't do anything. Can someone help me and I don't need links to support articles because I have read all of them.

Are you able to sync over the wire first, that must be done FIRST in order to establish the first sync.