Should i reboot my tethered jailbroken device for this tweak?

I recently jailbroke my iphone and am new to the whole concept of jailbreaking. I installed a tweak, and it wants me to reboot my phone so it will work. However, since i have a tethered jailbreak, if i turn off my phone i will lose my jailbreak and will have to boot it tethered. If i reboot my phone for the tweak to take effect, if i boot tethered will the tweaks i downloaded still be there?

Yes they will be its only because its a tethered you reboot and have your tweaks and themes.

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