Why can't anyone hear me when I make a call on my Iphone 4?

It doesn't seem to matter what I do. I can put headphones in that have a mic, I can use speaker and I can put it on normal calling but nobody can ever hear me. Is this a hardware or software issue? I just spent a week with no phone and got a new one and it has this issue. What exactly are solutions to this?

I had this problem before. Your mic might be messed up call apple

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