Are there any big major differences between the iPhone 4 and iPhone 5?

Are there any big major differences between the iPhone 4 and iPhone 5?

Not really just a better camera and panorama

No. Just size. The iPhone 5 is more slim, and longer.

For me the biggest annoyance between the iPhone 4&5 is the dam charging/docking plug, I can't use my phone with any of my sound system docks and I also have fifty million iPod / iPhone USB cables witch I can't use on the iPhone 5. (I don't actually have 50, 000, 000, just 5)