Is there a way i can make an iphone 4 nonusable that was stolen?

One of our phones an iPhone 4, was stolen. Is there a way I can make this phone nonusable with the serial number or ESN?

Like I said before.
If you have an iCloud account AND have 'Find my iPhone' installed on the phone do this.
https://www.icloud.com/...cloud.com/
It will have to be on and have power.
If you don't, not a lot of other options. Best luck.